The oldest viruses in the world.

Viruses currently dominate public concern and are ubiquitous in all forms of life. Their origins remain a mystery, but they have persisted for millions of years, constantly adapting. While some are benign, others cause immense damage and claim countless lives. For better or worse, viruses are an enduring aspect of existence, impossible to completely eradicate. (Image: Unsplash)

by TOI Lifestyle Desk

Endogenous retroviruses (ERV)

ERVs are remnants of retroviral infections that have integrated into the genomes of their host organisms over millions of years. They provide information about ancient viral infections and interactions between the virus and the host. (Image: Unsplash)

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Hepatitis B virus (HBV)

HBV is one of the oldest known viruses and evidence of infection dates back thousands of years. Ancient DNA studies have revealed HBV sequences in mummified human remains, providing insight into its ancient prevalence. (Image: Unsplash)

Human papillomavirus (HPV)

HPV is another ancient virus that has likely infected humans for millennia. Ancient DNA studies have identified HPV sequences in ancient human populations, shedding light on its historical impact. (Image: Unsplash)

Herpesvirus

Several herpesviruses, including herpes simplex viruses (HSV) and Epstein-Barr virus (EBV), have ancient origins and have co-evolved with their host species for millions of years. (Image: Unsplash)

Flu virus

Influenza viruses have likely been infecting vertebrates for millions of years. Studies of ancient viral RNA preserved in permafrost have revealed information about ancient strains of influenza virus. (Image: Unsplash)

Polyomavirus

Polyomaviruses are a family of ancient viruses found in several vertebrate species, including humans. Ancient DNA studies have identified polyomavirus sequences in ancient human populations. (Image: Unsplash)

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Poxvirus

Poxviruses, including the variola virus (the causative agent of smallpox), have ancient origins and have probably been infecting humans for thousands of years. Studies of ancient DNA have provided insight into the history of smallpox. (Image: Unsplash)